A relação da deficiência de vitamina D e a depressão em crianças e adolescentes: uma revisão da literatura

Abstract

Depression is a mental pathology that triggers behavioral, psychological and physical changes in an individual. It is considered the psychiatric syndrome with the highest prevalence worldwide, affecting individuals of different age groups, including children and adolescents, which has stood out as a group with a high prevalence of the pathology. It has been reported that patients with depression are deficient in several nutrients, including Vitamin D. This vitamin has been correlated with depressive disorders and several studies have investigated whether its deficiency is associated with depression, as well as whether supplementation can benefit the treatment of depression. . With that, the object of the present work was to carry out a review of the literature in the studies that analyze the relationship of Vitamin D deficiency in children and adolescents. To this end, a search was carried out on Pubmed, considering the articles published in the last 10 years. Twelve articles were found, including observational and clinical studies. The results showed conflicting data, in which some studies attest to a correlation between Vitamin D deficiency and depression, while in others this was not verified. Another trend observed was that the effect of Vitamin D was more pronounced in more severe manifestations of depression. More randomized and controlled clinical studies are needed to verify the association of Vitamin D deficiency and depression in children and adolescents.