Multirresistência de Klebsiella pneumoniae, Pseudomonas aeruginosas e Staphylococcus aureus em hemoculturas em UTIs: uma revisão de literatura

Abstract

The bacteria Klebsiella pneumoniae, Pseudomona aeruginosa and Staphylococcus aureus are targets of concern for the scientific community because they carry strains that give them characteristics of multidrug resistance. In addition to transferring or acquiring other resistances, one of the causes of this exacerbated increase occurs through the excessive use of antimicrobials in nosocomial and community settings. In this sense, the objective of this research is to analyze the multidrug resistance of the microorganisms Klebsiella pneumoniae, Pseudomonas aeruginosas and Staphylococcus aureus in blood cultures. The methodology used comprised a narrative bibliographical research, of an applied nature, based on the analysis of scientific studies. The research carried out demonstrates that the studied species are of great importance in Health Care Related Infections and in Primary Laboratory Bloodstream Infections. They present a list of resistances among the antimicrobials available for use in Brazil. Klebsiella pseudomonas is resistant to carbapenems, colistins, ampicillin (100% resistance), polymyxin, and cephalosporins. Staphylococcus aureus is resistant to oxacillin (reaching 100% resistance in some cases) and methicillin, with no resistance to vancomycin. And Pseudomonas aeruginosa is pan-resistant in 30.8% of cases and, specifically, is resistant to carbapenem and ceftadizime (100% resistance). In view of this, it is concluded that all of them have a high power of virulence and resistance, being bacteria that need continuous monitoring