Eficácia clínica do uso de própolis como adjuvante ao tratamento da periodontite: uma revisão de escopo

Abstract

Introduction: Periodontitis is a chronic inflammatory condition that affects more than half of the world's population and is associated with microbial imbalances and an exacerbated host immune response. Although non-surgical periodontal therapy (NSPT) is the conventional treatment, its efficacy may be limited, encouraging the use of adjuvant therapies. Objective: To evaluate the efficacy of propolis as an adjuvant to the treatment of periodontitis, especially in reducing clinical parameters, compared to placebo or chlorhexidine. Methodology: This scoping review was conducted according to the PRISMA-ScR guidelines, using the PUBMED database, and selecting studies that compared the use of propolis with placebo or topical chlorhexidine in the treatment of periodontitis, only adults over 18 years of age participated. Results: Nine randomized controlled clinical studies were included, where the results showed significant benefits of the use of propolis, both in topical and systemic applications, with demonstrated antimicrobial, anti-inflammatory and antioxidant properties. Studies also indicated its potential in patients with type 2 diabetes, with improvement in metabolic and periodontal parameters. Despite the promising results, methodological limitations and the risk of bias compromise the robustness of the evidence. Conclusion: It is concluded that propolis is a promising adjuvant therapeutic alternative, but more rigorous clinical trials are needed to validate its efficacy and safety in the management of periodontitis.