Sarcopenia e estado nutricional no lúpus eritematoso sistêmico

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease whose etiopathogenesis, which is not yet well understood, involves multiple genes, hormonal and environmental factors. During periods of exacerbation and remission, SLE directly and indirectly compromises nutritional status and body composition. The objective of this study was to evaluate the association between sarcopenia and nutritional status in women with SLE who are assisted by a teaching hospital in Maceió, Alagoas. A cross-sectional analysis of the socioeconomic, demographic, clinical, anthropometric and sarcopenia data of 43 adult patients, selected for convenience, was performed. The anthropometric evaluation included data on circumferences, skin folds, fat percentage and body mass index (BMI). The assessment of sarcopenia followed the protocol proposed by the European Working Group on Sarcopenia in the Elderly-EWGSOP (2019). The data were compensated with the aid of the statistical package SPSS 20.0, adopting the 95% confidence interval. Pearson's chi-square test was applied, adopting a significance level of p> 0.05. Sarcopenia was not detected, despite the low handgrip strength (HGS) identified in 21.4% of the patients, among whom 66.6% were overweight, and the reduction in physical performance, with no statistical differences according to degrees of BMI. These findings call attention to the need for further studies to investigate the role of overweight / obesity on the quantity and / or muscle skeletal function of adult women with SLE.