Estudos clínicos dos efeitos cardiovasculares do Allium sativum (alho): uma revisão da literatura

Abstract

Cardiovascular diseases are characterized by affecting the quality of life of people affected in their various areas, and are also considered the main cause of death in the world. In this sense, strategies aimed at improving the quality of life of these people are of great social relevance. In this way, medicinal plants emerge as an alternative, since they have been reported since ancient times as man's allies for relieving various pathologies. Among these, garlic (Allium sativum) is considered an excellent medicinal plant due to its varied therapeutic applications, mainly in cardiovascular diseases. Therefore, this work brought together the main studies carried out in humans regarding the application of this plant in the cardiovascular system. This research was developed from searches in the PubMed database. Commands such as: Allium sativum clinical screening, Allium sativum clinical case and Allium sativum in the cardiovascular system of humans were used, limited to articles published in the last 10 years (2010-2023). In total, 72 articles were researched, but only 5 were chosen for the discussion of the results. All selected articles were carried out on humans with varying numbers of people and garlic dosages. It was observed that the administration of Allium sativum in patients with some dysfunction in the cardiovascular system has beneficial effects such as improvement in atherosclerosis, improvement in endothelial function, improvement in vascular elasticity, reduction in atherogenicity of blood serum, reduction in low attenuation coronary arterial plaques, decreased oxidative stress and decreased LDL, which infers that this active ingredient can be considered, in the near future, as an alternative for the treatment of cardiovascular diseases.