Avaliação da qualidade metodológica das revisões sistemáticas sobre aplicação da toxina botulínica no tratamento das disfunções temporomandibulares

Abstract

The temporomandibular disorders are pathologies that manifest painful symptoms and can lead to degeneration of the temporomandibular joint, whose treatment is based on symptom control. Botulinum toxin has gained prominence for being a noninvasive and reversible therapeutic strategy, being widely used for presenting a significant performance to treat muscular hyperactivity disorders. However, its use for the treatment of temporomandibular disorders is still considered an off-label tool. Objective: According to that, the aim of this study was to evaluate the methodological quality of published systematic reviews that deal with the application of the toxin in these disorders. Material and Method: A comprehensive review was conducted and systematic reviews with or without meta-analysis on the application of botulinum toxin in the treatment of temporomandibular disorders were eligible. The search was performed by two reviewers in the following databases: MEDLINE via PubMed, Embase, Scopus, Web of Science, DARE-Cochrane and SIGLE via OpenGrey. The reviewers performed all data extraction and selection independently, in case of disagreement, a third reviewer was consulted. The AMSTAR 2 instrument was used to classify the methodological quality of the reviews. Results: Among the systematic reviews included, six had a critically low methodological quality and one review exhibited a low methodological quality. Conclusion: In summary, the results of this study made it possible to affirm that its findings should be reviewed with caution. Thus, it can be concluded that the results do not provide statistical confirmation to recommend or no the label use of botulinum toxin to treat temporomandibular disorders.