Efeitos anti-hipertensivos da Alpinia Zerumbet (Colônia): uma revisão da literatura

Abstract

Hypertension is a condition with a multifactorial, chronic and non-transmissible cause that affects millions of people and the cause of cardiovascular events that leads to a large number of hospitalizations and in many cases leading to death. There are several classes of drugs to treat SAH, such as beta-blockers, vasodilators, diuretics, angiotensin-converting enzyme inhibitors, among others. As a supporting alternative to help control blood pressure, we have Alpinia zerumbet, a plant for medicinal use with hypotensive action, originally from India and Asia. In Brazil it is found in the Northeast and in other regions where the favorable climate for its cultivation is tropical and subtropical, being known as colony. From this, the objective of this work was to carry out a bibliographical survey about the plant species Alpinia zerumbet and its antihypertensive effect. For this, a literature review was carried out in the Pubmed database, with publications between 2003 and 2020. In all, nine articles were found, of which six did not correspond to the inclusion criteria. Three articles were selected which, in general, presented in-vitro and in-vivo tests with rats. In general, everyone concluded the antihypertensive action of Alpinia zerumbet in their work. These studies demonstrated that this plant lowered blood pressure in rats submitted to induced or non-induced hypertension with the purpose of making a comparison between the use of essential oil, hydroalcoholic extract and the methanolic fraction of the plant and the drugs and/or substances used in the tests. to verify if there was interference in the antihypertensive action as well as effect on hypotension caused by the plant substances mentioned above. In this way, we conclude that Alpinia zerumbet has antihypertensive action and that it may act as an adjunct in the control of blood pressure, contributing to the control of hypertension.