Avaliação das terapias disponíveis e da taxa de recidiva diante do tratamento do ceratocisto odontogênico

Abstract

The Odontogenic Keratocyst (OC) is a cyst with an aggressive clinical behavior, which was previously considered an odontogenic tumor and which, due to the inclusion of marsupialization as a treatment, is now considered a cystic lesion. This work aims to study the most recent systematic reviews and relate the treatment performed with the rate of recurrence in patients with OC. Extensive searches were then carried out in the databases of PubMed, MEDLINE, Scopus, Web of Science, Embase and The Cochrane Library, where after evaluating the inclusion and exclusion criteria, 6 systematic reviews were selected for the present study. Enucleation alone had a recurrence rate of 23.5%, followed by curettage had a recurrence rate of 18.5%, enucleation + marsupialization 13.8%, enucleation + cryotherapy 12.9%, enucleation + carnoy solution 10%, that is, in all cases in which there was an association with only one adjuvant technique, the rate of lesion recurrence decreased from 21.3% to 67.5%, as in the case of the comparison between enucleation alone and enucleation with Carnoy's solution. There is no reason to perform enucleation or marsupialization alone, as both have a considerably higher rate of recurrence than the same treatments with some adjuvant therapy, especially when associated with Carnoy's solution, and if the patient is uncooperative or the cyst has already recurred at least 3 times, resection is recommended.