Influência do tratamento periodontal no controle metabólico de pacientes com síndrome metabólica e periodontite: revisão sistemática

Abstract

Although the primary etiological factor of periodontal disease is the bacterial biofilm, the host response and the presence of systemic diseases seem to be associated with its development. The reduction of systemic inflammation through the elimination of periodontal disease in individuals with metabolic syndrome, by the dental surgeon, may reduce the risk for cardiovascular disease and diabetes. The aim of this systematic review is to answer the following focus question: In patients with MetS and periodontitis, is NCPT associated with systemic antimicrobials more efficient than NCPT alone in helping to reduce systemic inflammation? Randomized controlled clinical studies comparing NCPT with or without systemic antimicrobials in the treatment of periodontitis were included. Searches were taken from the following electronic databases: PubMed, Scopus and Web of Science. Five articles were selected for full reading and only 2 were elected for review. The result of one study revealed that antibiotic therapy associated with NCPT reduced systemic inflammatory parameters in the test group compared to the control group, on the other hand, the other assay showed NCPT as the main reducing factor of inflammation, since both groups obtained a significant reduction in inflammatory parameters. It is imperative to conduct more randomized clinical trials and systematic reviews to determine whether or not this association should be recommended.