Desenvolvimento de membranas de nanofibras biodegradáveis de PCL contendo óleo essencial de rosa mosqueta

Abstract

Rosehip essential oil is recognized and used by the cosmetics industry for having hydrating, healing and cellular regenerative pharmacological properties, which benefit from intact skin to damaged skin. Due to these characteristics, in this study, nanofiber membranes were prepared with rosehip essential oil and PCL (polycaprolactone), a biodegradable and non-toxic polymer. The electrospinning technique was used, aiming at the production of biomimetic structures in the extracellular matrix of the skin. Therefore, different concentrations were studied for the formation of membranes, the structures formed were morphologically analyzed by SEM (Scanning Electron Microscopy). It was possible to measure and determine the average diameters of the nanofibers present in the membranes, having average diameters between 1026.4nm (pure PCL) to 1346.0nm (PCL with 20% oil). Thus, nanostructured membranes composed of a biodegradable and non-toxic polymer were developed, containing concentrations of 5%, 10% and 20% of rosehip essential oil, aiming at a possible application in the health area.