Perfil sócio-demográfico, clínico-nutricional e glicêmico em porta-dores de diabetes mellitus tipo 2 com e sem microalbuminúria

Abstract

Introduction and objectives: Microalbuminuria (MA) is characterized by elevated urinary albumin excretion below the levels of proteinuria characteristic. Not detected by routine examinations, but there is evidence of the prognosis between the occurrence of MA and the development / evolution of vascular complications in DM. Accordingly, the objective was to determine the socio-demographic, clinical, nutritional and glycemic control in subjects with T2DM, factors that are inputs in the development of complications in type 2 diabetes in individuals with and without MA. Methods: 49 participants with type 2 diabetes, age over 20 years, absent of microvascular, macrovascular, and proteinuria were divided into two groups: normoalbuminuria, which accounted for 71.4% (group NMA) and 28.5%, microalbuminuria (MA group ).We collected socio-demographic variables: age, gender and family income; clinical and nutritional data such as BMI (WHO, 1995); Waist Circumference-CC-; risk factors: abdominal adiposity-AA-, alcohol use, smoking and sedentary lifestyle, and comorbidities: hypertension, dyslipidemia and hypertension. The glucose profile (GP) was determined from the analysis of three parameters: fasting plasma glucose (FPG), postprandial glucose (PPG) and glycated hemoglobin (HG). Results: Participants were predominantly female, low income and at risk for obesity. Most are hypertension, dyslipidemia and has no access to specific nutritional therapy. Showed a profile with poor glycemic values above the therapeutic targets. Among diabetics with microalbuminuria (MA), only 7.7% had values between four and six per cent, most of microalbuminuria (92.3%) also had high values for A1c, with a minimum of 5.6% and maximum value 12.1%. The average weight was 8.3 ± 1.98%. Comparing the groups is observed that there was no statistically significant difference (p = 0.354) but the estimated risk (odds ratio) for the occurrence of microalbuminuria (MA) was relevant the higher the values of A1c (OR = 2.769 ). Conclusions: The findings predispose participants to cardiovascular disease and highlights the difficult control of diabetes and its complications, including worsening of microalbuminuria is already present.