Potencial toxicológico e o impacto do piriproxifeno nos parâmetros zootécnicos de tilápia do nilo (Oreochromis niloticus, Linnaeus, 1758)

Abstract

Fish farming is one of the world's fastest growing activities, with emphasis on the cultivation of Tilapia in lakes and dams, and therefore the exposure of the chemical released in these water bodies is vulnerable. The objective of this work was to determine the 50% lethal concentration (LC50-24 and 96h) of commercial formulations of Pyriproxyfen in different concentrations, as well as their impact on zootechnical performance, locomotive behavior, and to assess their toxicological potential in Nile Tilapia Oreochromis niloticus). An acute toxicity test was performed to determine LC50-24 and 96h with 09 treatments in duplicate in 18 20L aquaria. The LC50-24 and 96h for Tilapia fingerlings were 10.70 mg / L and 2.77 mg / L, respectively. Chronic toxicity test in the 96h exposure period for quantification of acetylcholinesterase with 04 treatments in triplicate in 12 20L aquaria along with video filming. Animals exposed to the concentrations of Piriproxifene in the period of 96h did not present alterations in their locomotive behavior. Animals exposed to different concentrations of Piriproxifene over the 96 hours presented significant differences in both protein concentration and specific activity of cerebral acetylcholinesterase. In the subchronic toxicity test with duration of 28 days of exposure, the animals submitted to the highest concentrations presented the worst performances. The video tracking demonstrated after 28 days decreased motor activity. More severe lesions in hepatic tissue were found at a concentration of 1.2 mg / L.