Proposta de protocolo para o tratamento de feridas cutâneas experimentais por meio de microcorrentes em ratos wistar

Abstract

Pressure ulcers are a public health problem, especially considering the impact they have for the sick person, the family and society. Furthermore, a quality indicator on health. At a time marked by a deep economic crisis, it is essential that health professionals understand the economic costs - tangible and intangible - associated with this problem. Pressure ulcers are a serious problem in that it causes a significant decrease in quality of life in patients and compromise the resolution of other health problems, including infections that can lead to death. Pressure ulcers are a common problem for many countries in the world, at all levels of health care, affecting people of all age groups and resulting in high economic costs, resource consumption, and also individual and family suffering. They carry a heavy cost investment in equipment necessary to curative care, as well as increased consumption of drugs, as well as any costs of surgery or prolonged hospitalization. The application of low amperage electrical stimuli promote the healing process in the body, especially those factors that retard or hinder the process. Considering the lack of standardization and the wide variability of these parameters for this type of low amperage current, the objective of this work is to propose a protocol for the treatment of experimental wounds through microcurrent. This is a prospective experimental study, which used 35 Wistar rats, which were randomly assigned by lot into 5 groups of 7 animals each. In all groups performed - if a dermal wound with a dermatological 8 millimeter punch circumference. In group 1 (control) the manipulation was performed with placement of electrodes without the application of microcurrent; Group 2 (10 uA) - Treaty with frequency 0.3 Hz and an intensity of 10 uA; Group 3 (30 uA) - Treaty with frequency 0.3 Hz and an intensity of 30 uA; Group 4 (100 uA) - Treaty with frequency 0.3 Hz and intensity of 100 uA; Group 5 (160 uA) - Treaty with frequency 0.3 Hz and intensity of 100 uA. Proposed treatments were initiated immediately after injury and applied daily for 14 days. After 14 days was removed a fragment of the lesion area for histological analysis by light microscopy. Statistical analysis was performed using ANOVA. For the variable thickness of the epithelium and keratin was no significant difference between the average in the comparison between the control group verses treatment groups, p = 0.0065. For the variable fibroblast area density profile was no significant difference between the average in the comparison between the control group verses 30 microamps, p = 0.0001. We conclude that the microcurrent is able to accelerate wound healing.