Hiperplasia fibroepitelial mamária felina

Abstract

Feline Mammary Fibroepithelial Hyperplasia (HFMF) is an abnormal enlargement of the mammary glands triggered by a progesterone disorder (P4). With the objective of supporting a research project to find the best therapeutic form, a literature review was performed. METHODS: For the review of the HFMF theme and the hormonal cascade of mammogenesis, articles were selected, after research done prioritizing the databases: CAPES, MEDLINE, PubMed, NCBI, Web of Science, books, among others that had publications of interest The contents were read and clinical observations were separated into the files, such as: age of the cats, use of contraceptive based on P4, onset of breast growth, clinical signs, description of macroscopy, diagnosis, therapeutics and prognosis; likewise separate data on mamogenesis. Results: A standardized therapeutic protocol to address HFMF has not yet been described in the literature; there is still a misunderstanding of the pathogenic mechanism; among the therapeutics, there is a varied priority between OVH, antiprogestin and mastectomy applied to the breasts with persistence of growth after OVH or with cutaneous ulceration and necrosis. Considerations: Because it is a benign pathology, the need for mastectomy needs to be discussed. The pathogenesis of HFMF is still open to research due to the interaction of physiological hormones of puberty, IGF-1 and nutritional aspect not yet investigated. Therapy is the main challenge and interpretation of the literature review demonstrates that wounds management (when present) associated with OVH may be sufficient; so a study was scheduled and conducted.