Cannabis medicinal como tratamento para epilepsia

Abstract

To carry out a literature review on the use of Cannabis in the treatment of epilepsy. A literature review was carried out by searching for bibliographic information accessible in the Virtual Health Library (VHL) of the Ministry of Health, as well as the PUBMED and SciELO platforms. The search terms used were Cannabis AND Epilepsy, Cannabis AND Epilepsy, Cannabidiol AND Medicinal Application, applying the filters: Controlled clinical trial and Observational study. After collecting the articles, the inclusion and exclusion criteria were applied. In this way, a total of 112 documents were identified; however, when using the inclusion and exclusion criteria, only 14 were chosen. Within this set, an analysis was carried out to determine which studies were randomized, considering both the pharmacological and clinical perspectives. CONCLUSION: It was observed that the therapeutic potential of Cannabis in the treatment of epilepsy is a promising area to be explored. It interacts with receptors that cause neuronal mediation, and cannabidiol in particular has less psychoactive effects, making it an excellent therapeutic alternative for epilepsy.