Perfil de sensibilidade de uroculturas realizadas em Maceió – AL

Abstract

The knowledge of the sensitivity pattern of urine cultures in a given region will facilitate treatment, reduce costs and may prevent the development of resistant pathogens. The objective of this work was to evaluate the profile of prevalence, sensitivity and resistance of microorganisms in urine cultures. There were 2949 urine cultures from two laboratories in the city of Maceió - AL, with a profile of out patients from January 2017 to December 2018. From the positive urine cultures, there was a higher prevalence in females (86.5%), with Escherichia coli being the most frequent pathogen (61.5%). The antibiotic with the lowest percentage of resistance in cultures that isolated E. coli was Amoxicillin with Clavulanate (95.1%). The most prevalent agent in childhood compared to other age groups was Proteus mirabilis, while in the elderly it was Klebsiella pneumoniae. Fromthe total, 169 samples showed Extended Spectrum Beta Lactamase (ESBL) producingmicroorganisms, with women and old patients being most affected. Of these bacteria, E. coli was the most frequent, whose prevalence of greater sensitivity was to Amikacin. In this study, it was concluded that UTI remains more prevalent in females, with Escherichia coli being the most frequent pathogen; Amoxicillin with Clavulanate was the drug of least resistance and we observed a 5.7% prevalence of ESBL microorganisms, being a point that deserves attention, once outpatients was the only patients profiles included in this study.