Acurácia de algoritmo para identificação de problemas relacionados a medicamentos em puérperas hospitalizadas com pré-eclâmpsia

Abstract

Preeclampsia is a multisystem disorder that affects women during pregnancy and, in addition to generating gestational hypertension and proteinuria, it brings severe complications in several organs. The evaluation of postpartum women's pharmacotherapy is of paramount importance in optimizing treatment and reduces the risks that drug-related problems can bring patients, however, few studies are found in the literature that discuss this topic. Because of this, the aim of this study was to determine the accuracy of an algorithm for identifying drug-related problems in puerperal women hospitalized with pre-eclampsia. For this purpose, a database of electronic medical records of 53 postpartum women hospitalized at the University Hospital Professor Alberto Antunes, approved by the ethics committee of the Federal University of Sergipe under CAE number: 55217416.1.1001.5546, was used. As an inclusion criterion, patients had to be hospitalized for at least 5 days. The analysis of the pharmacotherapy of the AMD was carried out by the author of this study, while the analysis using the PWDT was carried out by two clinical pharmacists. A gold standard was created by the supervisor of this study, for later accuracy analysis. To measure it, a commission of specialists was responsible for the calculations. 100 DRPs were identified, with effectiveness being the most common. The mean blood pressure was 155/96 mmHg, the mean number of drugs prescribed was 4 per patient. The accuracy of the tools was 0.59, sensitivity 0.79 and specificity 0.17. In the end, it was possible to conclude that the DAM was the tool that presented the best accuracy results and that, despite the low specificity values, the sensitivity was satisfactory. In addition, it was observed that the effectiveness DRPs increased the patients' hospital stay by one day. Therefore, it is necessary to carry out robust studies to more clearly assess the relevance of using methods to identify DRPs in puerperal patients.