Efeito diurético da Hibiscus sabdariffa L. sobre o volume urinário e o perfil eletrolítico de sódio, potássio e cloro: uma revisão de literatura

Abstract

The kidneys are paired organs that perform a variety of functions, including regulating water and electrolytes. In this way, good kidney function contributes to the body's balance and any alteration in its function suggests pathologies that are harmful to survival. Therefore, new discoveries are necessary for the engineering of new therapeutic guidelines. Medicinal plants, due to their vast composition of phytochemicals, are a promising alternative for this purpose, so that several medicinal plants have renal effects and should be widely studied. Hibiscus sabdariffa L. is a plant well known for its many scientifically proven pharmacological effects, among which are its diuretic activity. This work was elaborated from searches on the platforms: Google Scholar, PubMed, Scielo and CAPES Journals Portal, starting in December 2022 and ending in April 2023. The keywords used for the research were: Hibiscus sabdariffa L., Hibiscus sabdariffa L. diuretic, Hibiscus sabdariffa L. pharmacological effects, mechanism of diuretic action Hibiscus sabdariffa L. A total of 85 articles were researched, among which only 9 were chosen for the study. These articles demonstrated the diuretic effects of Hibiscus sabdariffa L, based on the evaluation of urinary volume and changes in serum and excreted electrolyte levels, using different experimental models, of which 67% used animals and 33% humans, using different dosages and extractions, of which approximately 50% were carried out with aqueous extract, 25% with dry extract, 13% with methanolic extract and 12% with aqueous infusion, from different parts of the plant, 56% being carried out with dry calyxes, 22% with dry petals, 11% with flowers and 11% with calyxes. It was observed that in all articles, HS produced an increase in urinary volume and changes in serum concentrations and excretion of electrolytes.