Qualidade da evidência da associação entre o índice inflamatório dietético e os marcadores da inflamação em indivíduos sem comorbidades: uma revisão sistemática de estudos observacionais

Abstract

The association between IID and inflammatory markers in the literature is divergent. This study aimed to evaluate the quality of evidence of the association between dietary inflammatory index and inflammation markers in individuals without comorbidities. For this, a systematic review of the literature was conducted in the LILACS, Scielo, PubMed and Scholar Google databases; the Joanna Briggs Institute methodological quality assessment tool of articles was used. A total of 5991 articles were identified up to August 2022 and of these, 9 were used for final review. The studies had wide variation in sample size, and reduced number of IID food parameters. Positive and significant associations were majority for C reactive protein only; predominantly no associations for TNF-⍺, IL-6 and IL10. Greater predictive power was observed for stratified IID data compared to continuous data and an overall weak to moderate strength of association. It is concluded that the predictive power as well as the quality of evidence for the association between IID and inflammatory markers is low; not exceeding the limits of food group indices. It is suggested the construction of an index that takes into account the magnitude of the association between individual food parameters and inflammatory markers, in an attempt to prioritize the accuracy of the tool.