Revisão das principais sínteses assimétricas do (+)-grandisol (feromônios do bicudo do algodoeiro) descritas na literatura

Abstract

The cotton boll weevil (Anthonomus Grandis) is considered the main cotton pest, having been introduced to Brazil in 1983. It is a pest that causes huge damage to crops and can lead to almost 100% of crop loss. Its control is somehow difficult due to its high reprodutive rate. One of the main ways to control this insect, according to integrated pest management, is based on the use of pesticides in crops, where there is a reduction in its population. The present work aims to use the pheromones in the fight against this cotton pest, through organic synthesis, with emphasis on the asymmetric syntheses of Grandlure 1, the main pheromone found in the pheromone mixture, formed by 4 basic structures . A bibliographic survey of the main asymmetric synthetic routes in the production of Grandlure 1, which is (+) - Grandisol, was performed and their respective global yields were discussed and compared according to the number of reaction steps. Thus, the synthesis of Grandlure 1, seeks to reduce the use of pesticides in crops, attracting and consequently exterminating the plague, without harming the environment and the farmer himself, avoiding their proliferation and increasing economic advantages.